Combinatorial Phage Library Screening for Estrogen Receptor Interacting Peptides and Applications to the Study of Xenoestrogen Biology and Pharmacology
نویسنده
چکیده
The steroid hormone estrogen is a key regulator of growth, differentiation and function of a wide variety of target tissues of diverse function. Estrogen plays a critical role in the development of the female reproductive system, in directing neuroendocrine control of ovulation, and in regulating female sexual behavior. In addition, however, this hormone clearly has functions in tissues other than those related to reproduction. Specifically, estrogen is involved in the development and maintenance of skeletal integrity and is an important regulator of triglyceride and cholesterol homeostasis in both males and females.
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